What Are Cytoplasmic Determinants


What is cytoplasmic determinants example?

The factors responsible for this early mapping out within zygotes of subsequent cell fate determination are termed cytoplasmic determinants. … They consist for example of stored mRNAs as well as proteins and various regulatory factors that found within the cytoplasm of the egg cell.

What are cytoplasmic determinants quizlet?

Terms in this set (6)

Cytoplasmic determinants. –maternal substances in the egg that influence course of early development. -after fertilization early mitotic divisions spread zygote’s cytoplasm into separate cells.

How do cytoplasmic determinants affect gene expression?

The main role of cytoplasmic determinants is the regulation of gene expression. Due to the uneven distribution of cytoplasmic determinants within the cytoplasm the daughter cells inherit different amounts of them during cell division. Therefore the gene expression in daughter cells may also differ from each other.

What are cytoplasmic factors?

Among these “cytoplasmic factors” are proteins and mRNAs that function during early development of the embryo. Both the stored proteins and new proteins made from stored mRNAs can be utilized to control cell functions during cleavage.

Where are cytoplasmic determinants?

Cytoplasmic determinants are special molecules which play a very important role during oocyte maturation in the female’s ovary. During this period of time some regions of the cytoplasm accumulate some of these cytoplasmic determinants whose distribution is thus very heterogenic.

What is the meaning of cytoplasmic?

: the organized complex of inorganic and organic substances external to the nuclear membrane of a cell and including the cytosol and membrane-bound organelles (as mitochondria or chloroplasts) Other Words from cytoplasm. cytoplasmic ˌsīt-​ə-​ˈplaz-​mik adjective.

How do cytoplasmic determinants and induction work?

Unlike the segregation of cytoplasmic determinants induction is an extrinsic process that depends on the position of a cell in the embryo. … Two identical cells can follow different fates if one is exposed to an external signal (often produced by a different cell) while the other is not.

What produces cytoplasmic?

Cytoplasmic determinants are also found in some post-embryonic cells where they produce cytoplasmic asymmetry (q.v.). In dividing cells this leads to asymmetric cell division in which each of the daughter cells differentiates into a different cell type.

How does inductive signaling lead to cell determination?

Cell determination usually takes place as a result of inductive signaling between nearby cells. … Differential gene expression refers to the ability of a given unspecialized cell to express different genes and therefore produce different proteins and structures found within that final specialized cell.

How do cytoplasmic factors affect cell differentiation?

The cytoplasm influences and controls the behaviour of nuclear genes and the differentiation of the cell. … Even after synthesis of protein the post transcriptional events may also be influenced by cell cytoplasm and may in turn leads to differentiation of cell cytoplasm.

Are cytoplasmic determinants transcription factors?

Cytoplasmic determinants

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Indeed asymmetric distribution of cytoplasmic regulatory factors necessary for specification (e.g. mRNAs and proteins such as transcription factors) can influence the fate of the daughter cells.

Do cytoplasmic determinants affect cell differentiation?

Cytoplasmic determinants affect cell differentiation by determining which regions of an embryo will form what structures.

What is cytoplasmic localization?

The cytoplasmic transport and localization of mRNAs is a post-transcriptional mechanism that restricts the synthesis of proteins to specific sites within cells. For years studies on mRNA localization were limited to a few localized transcripts in a small number of model systems.

Is Bicoid a cytoplasmic determinant?

Remember the bicoid mRNA is the cytoplasmic determinant while the Bicoid protein is the morphogen. … These experiments prove that bicoid mRNA and thus Bicoid protein are both necessary and sufficient to specify anterior pattern. Bicoid was the first “morphogen” regulating embryonic development to be identified.

How cytoplasmic determinants determine the fate of blastomeres?

Cytoplasmic de- terminants are differently segregated into each blastomere during cleavage and fix the develop- mental fate assumed by the cells that inherit them. In this case presence of cytoplasmic determinant in a cell is all that is needed to determine the fate of the cell.

Can cytoplasmic determinants be RNA?

These cytoplasmic determinants appear to be in part maternal messenger RNA molecules.

How does the blastocyst develop?

In humans blastocyst formation begins about 5 days after fertilization when a fluid-filled cavity opens up in the morula the early embryonic stage of a ball of 16 cells. … About seven days after fertilization the blastocyst undergoes implantation embedding into the endometrium of the uterine wall.

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Are blastomeres identical?

During the first few cleavage divisions the blastomeres are spherical and totipotent (genetically identical) with the overall size of the developing embryo remaining the same. … Further TE differentiation will result in the formation of the placenta whereas the ICM will develop into the embryo proper.

What are cytoplasmic processes?

Cytoplasmic processes extending from the basal surface of the normal basal cell are different from processes in the intercellular space. … The basal surface of the basal cells is mainly flat and devoid of cytoplasmic processes (Fig. 1). The basement membrane is continuous and associated with aperiodic fibrils.

What are the cytoplasmic organelles?

Cytoplasmic organelles are “little organs” that are suspended in the cytoplasm of the cell. Each type of organelle has a definite structure and a specific role in the function of the cell. Examples of cytoplasmic organelles are mitochondrion ribosomes endoplasmic reticulum golgi apparatus and lysosomes.

What are cytoplasmic enzymes?

So the researchers created a cell-free system that includes neutrophil nuclei and dollops of cytoplasm from the cells. … They found that two enzymes stashed in cytoplasmic granules enter the nucleus and join forces to unwind the chromatin.

What is cytoplasmic specification?

A fertilized egg contains cytoplasmic components that are unequally distributed within the egg. … These different cytoplasmic components are thought to contain morphogenetic determinants that control commitment of the cell to a particular cell type.

What is the role of morphogens in development?

Morphogens are substances that establish a graded distribution and elicit distinct cellular responses in a dose dependent manner. They function to provide individual cells within a field with positional information which is interpreted to give rise to spatial patterns.

What determines cell fate?

Cell fate can be determined by endogenous developmental factors interaction with adjacent cells or external long-distance signals such as morphogens and hormones.

What is the role of nucleus and cytoplasm in development?

The nucleus is a cell’s central organelle which contains the cell’s DNA (Figure 3.6). The cytoplasm is composed of two parts the cytosol and organelles. Cytosol the jelly-like substance within the cell provides the fluid medium necessary for biochemical reactions.

What is gastrulation biology?

Gastrulation is defined as an early developmental process in which an embryo transforms from a one-dimensional layer of epithelial cells (blastula) and reorganizes into a multilayered and multidimensional structure called the gastrula.

How is morphogenesis controlled?

Morphogenesis is controlled by a “toolkit” of genes which switch development on and off at precise times and places. Here gap genes in the fruit fly are switched on by genes such as bicoid setting up stripes which create the body’s segmental form.

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What is the main goal of gastrulation?

The purpose of gastrulation is to position the 3 embryonic germ layers the endoderm ectoderm and mesoderm. These layers later develop into certain bodily systems.

What is determination and differentiation?

Determination and differentiation are processes that are coupled during embryogenesis where a small number of pluripotent cells (stem cells) expand and enter pathways through which they form the diverse cell types of the adult.

What happens first determination or differentiation?

Explanation: Once a committed cell begins to develop specialized functions it is known as differentiation. Before a cell differentiates it makes a commitment to a certain cell type first by specification which is reversible and then by determination which is irreversible.

What determines stem cell differentiation?

Embryonic stem cells (ESCs) are pluripotent cells that differentiate as a result of signaling mechanisms. These are tightly controlled by most growth factors cytokines and epigenetic processes such as DNA methylation and chromatin remodeling. … Adult or ‘somatic’ stem cells are thought to be undifferentiated.

What are two factors that affect cell differentiation?

The two factors that affect how cells differentiation is distance and energy.

What controls cellular differentiation?

Cellular differentiation is often controlled by cell signaling. Many of the signal molecules that convey information from cell to cell during the control of cellular differentiation are called growth factors. … Cells and tissues can vary in competence their ability to respond to external signals.

What is genomic equivalence?

The presence of identical genes in cells that are radically different from each other is known as “genomic equivalence. … If the genome is the same in all somatic cells within an organism (with the exception of lymphocytes see Sidelights and Speculations) how do cells become different from one another?

Cytoplasmic Determinants and Inductive Signals


AP Biology #63 – Cytoplasmic Determinants and Cell Differentiation

Differential Gene Expression | Cytoplasmic Determinants | Asymmetric Cell Division

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