What is Facultative Anaerobe ITs Definition And Example?

Facultative Anaerobe Definition

A facultative anaerobe is an organism that can survive in the presence of oxygen, can use oxygen in aerobic respiration, but can also survive without oxygen via fermentation or anaerobic respiration. Most eukaryotes are obligate aerobes, and cannot survive without oxygen.

Prokaryotes tolerate a wide range of oxygen, from obligate anaerobes which are poisoned by oxygen, to facultative anaerobes and obligate aerobes. Some prokaryotes are even aerotolerant, meaning they can survive in oxygen, but use anaerobic pathways for energy.

A facultative anaerobe can experience the best of both worlds. In times of low oxygen, a facultative anaerobe can use fermentation or anaerobic respiration to create ATP for the cells, typically still from the breakdown of glucose.

The only real difference in these pathways from aerobic respiration is that they use a different electron receptor at the end of the pathway. Aerobic respiration relies on oxygen to accept electrons at the end of the electron transport chain. A facultative anaerobe can use a variety of other pathways to deal with these extra electrons, as discussed in the examples.

It should be noted that facultative anaerobes are sometimes referred to as facultative aerobes. The terms are generally interchangeable.

Examples of a Facultative Anaerobe


A common facultative anaerobe is a yeast, used in various cooking applications such as making bread or beer. In either case, this facultative anaerobe must function without oxygen. Yet, the yeast can still survive, and must for these products to come outright.

In bread, yeast is responsible for making the bubbles in the dough. These pockets of air make the bread light and fluffy. Otherwise, the bread would bake into a solid mass more like a cake or brownie. Yeast creates these air pockets through the release of carbon dioxide, a byproduct of converting the glucose in the dough into energy.

For a lighter, more airy dough chefs often let the dough “rise”. This term simply means setting the yeast-laden dough in a warm place and allowing the facultative anaerobe to do its work. Over the course of an hour or so, the yeast will create large amounts of carbon dioxide within the dough, expanding it and making it lighter.

In beer, wine, and other alcoholic beverages, yeast is the key ingredient. The process of fermentation, or the creation of alcohol, occurs in yeast when they have plenty of sugar but little oxygen. Brewers and winemakers use this aspect of the facultative anaerobe to generate the alcohol within their products. Aerobic respiration completely reduces glucose to a few recyclable molecules and carbon dioxide.

Fermentation, on the other hand, leaves a final product: ethanol. Beer and winemakers create ethanol (alcohol) in their products by strictly controlling the amount of sugar and oxygen in their fermentation tanks. In these conditions, any facultative anaerobe will resort to fermentation, and put off ethanol as a byproduct. When the alcohol reaches the proper level in the mixture, the yeast is filtered out and the drink is bottled.


While most think only of small, single-celled facultative anaerobes, several larger groups of animals have evolved the ability to survive without oxygen. One of these, the mollusks, has a group of organisms that have adapted to regularly survive stints without oxygen.

Mussels often found in intertidal areas, experience daily shifts in their access to water. When the tide drops, the mussels become exposed to the air and must close their shells to avoid drying out. In some areas, the tide can go out for significant periods of time. The mussels cannot open their shells to get oxygen, or risk drying out and dying of dehydration.

To solve their conundrum, mussels have evolved the abilities of a facultative anaerobe. Instead of relying on their normal aerobic respiration when the tide goes out, the mussels switch to a form of energy that breaks down amino acids. This allows the mussel to survive hours, or even days, without getting a fresh source of oxygen.

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