What Is The Function Of The Organic Matrix In Bone


What Is The Function Of The Organic Matrix In Bone?

What is the function of the organic matrix in bone? The organic matrix provides flexibility (and strength). Name the important organic bone components. The most important organic bone components are cells collagen fibers and ground substance (proteoglycans and glycoproteins).

What is the function of the organic part of bone matrix?

The organic component of the bone matrix helps resist tension whereas the inorganic component helps resist compression.

What is the organic matrix in bone?

Collagen is the principal organic matrix in bone. The triple helical region of the molecule is 1014 amino acids long. In fibrils these molecules are staggered axially by integers of 234 residues or 68 nm (D).

What is the purpose of bone matrix?

Bone matrix constitutes a complex and organized framework that provides mechanical support and exerts essential role in the bone homeostasis. The bone matrix can release several molecules that interfere in the bone cells activity and consequently has a participation in the bone remodeling [117].

What is organic matrix?

When the inorganic portion of a bone is dissolved with acid there remains a model of the bone in a coherent elastic material that is sometimes referred to as the organic matrix. The term matrix which is widely used in descriptive anatomy is derived from a Latin word meaning womb or uterus.

What is the function of the organic matrix in bone and name the important organic bone components?

Bones constantly store and release calcium phosphate proteins and other matrix components of bone. Within the matrix the mineral crystals resist compression but are very brittle. The organic components such as the collagen fibers and the cells help give the bone some flexibility.

What are the components of the organic bone matrix and what is its function?

Bone a calcified tissue composed of 60% inorganic component (hydroxyapatite) 10% water and 30% organic component (proteins) has three functions: providing mechanical support for locomotion protecting vital organs and regulating mineral homeostasis.

What does bone matrix mean?

Bone matrix is a composite material consisting of organic and inorganic components. The organic matrix makes up ∼20% of the wet weight of bone and is comprised primarily of collagen. … Collagen gives bone its flexibility whereas the addition of mineral to the collagen network provides bone with its stiffness.

What is inorganic and organic matrix of bone and how do each of these matrices help to strengthen bones?

The inorganic matrix gives the rigidity and hardness to bone and is composed of a combination of calcium and phosphorus salts called hydroxyapatite. The organic collagen fibers give a bone its tensile strength and resistance to stress.

How does bone matrix differ from matrix of cartilage?

Cartilage and Bone are specialised forms of connective tissue. They are both made up of cells embedded in an extracellular matrix. … Cartilage is thin avascular flexible and resistant to compressive forces. Bone is highly vascularised and its calcified matrix makes it very strong.

What makes up the organic and inorganic portions of bone?

Organic part of bone is a protein Ossein and Collagen fibres. Inorganic part of bone is mainly Calcium Phosphate. The inorganic mineral is responsible for its hardness.

What are the cells that secrete the organic components of the bone matrix called?

Osteoblasts are bone cells that are responsible for bone formation. Osteoblasts synthesize and secrete the organic part and inorganic part of the extracellular matrix of bone tissue and collagen fibers.

What digests bone matrix?

Osteoclasts function in the resorption of mineralized tissue and are found attached to the bone surface at sites of active bone resorption. Their characteristic feature is a ruffled edge where active resorption takes place with the secretion of acid and bone-resorbing enzymes which digest bone mineral and bone matrix.

What is organic matrix composed of?

The organic matrix is composed of the bone cells that you have just learned about and of protein. Ninety percent (90%) of bone protein is Type I collagen which has a triple helical structure and ten percent (10%) consists of noncollagenous proteins.

What are organic matrix composites?

Composite materials or more simply composites can be defined as materials resulting from the association of a continuous phase known as a matrix and a dispersed phase called strengthening directed in a specific manner and mainly contributing mechanically.

What is the organic portion of bone tissue called?

The mineralized matrix of bone tissue has an organic component of mainly collagen called ossein and an inorganic component of bone mineral made up of various salts. Bone tissue is a mineralized tissue of two types cortical bone and cancellous bone.

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What is the function of osteoblasts osteoclasts and osteocytes?

They line the surface of the bone. These old osteoblasts are also called LINING CELLS. They regulate passage of calcium into and out of the bone and they respond to hormones by making special proteins that activate the osteoclasts. OSTEOCYTES are cells inside the bone.

What are the major organic and inorganic constituents of cartilage?

The organic matrix or ground substance consists of collagen fibers for the most part. The inorganic component mostly consists of calcium salts calcium phosphate (85%) calcium carbonate (10%) and small amounts of calcium and magnesium flouride.

What is the main function of the bone?

Bones: Bones of all shapes and sizes support your body protect organs and tissues store calcium and fat and produce blood cells.

What is the function of calcium salts?

Calcium salts are used as a source of calcium cation for the treatment or prevention of calcium depletion when dietary measures are inadequate.

Why are both organic and inorganic materials required for bone tissue to function normally?

Both are required for bone tissue to function because both work together to make the bone strong. … If only the inorganic matrix was intact then the bone would be brittle and shatter.

Which of the following components of the bone matrix is responsible for its hardness compressive strength?

Organic components being mostly type 1 collagen. Inorganic components including hydroxyapatite and other salts such as calcium and phosphate. Collagen gives bone its tensile strength namely the resistance to being pulled apart. Hydroxyapatite gives the bones compressive strength or resistance to being compressed.

What cells and matrix are found inside the bone?

Like cartilage and other types of connective tissue bone is made up of Cells and Extracellular matrix: Cells – which in bone are called osteoblasts and osteocytes (osteo – bone). There are also two other cell types: osteoprogenitor cells and osteoclasts.

Which of the following is the organic part of bone matrix composed of mostly collagen fibers?

The organic component is osteoid which is produced by osteoblasts. Osteoid is composed of both collagen protein plus a semisolid ground substance of proteoglycans (including chondroitin sulfate) and glycoproteins that suspends and supports the collagen fibers.

Which of the following cells function to maintain bone matrix quizlet?

Osteoblasts are bone forming cells they are matrix synthesizing cells responsible for bone growth. What is the function of Osteocytes? Osteocytes are mature bone cells that maintain the bone matrix. They act as stress or strain sensors and occupy the lacunae.

What is the definition of matrix in biology?

In biology matrix (plural: matrices) is the material (or tissue) in between a eukaryotic organism’s cells. The structure of connective tissues is an extracellular matrix. Finger nails and toenails grow from matrices. … It is generally used as a jelly-like structure instead of cytoplasm in connective tissue.

What accounts for the majority of bone inorganic matrix?

Organic matrix is 40 % of dry weight of bone tissue and 90 % of this type of matrix is formed by collagens (mainly type 1). 60 % of the dry weight of the bone is inorganic matrix that contains calcium hydroxyapatite and calcium phosphate.

What is the function of the matrix in hyaline cartilage?

Abstract. Hyaline cartilage is found in the synovial joints and assists the motion of joints. It is composed of chondrocytes and extracellular matrix. Chondrocytes plays a major role in the organization of extracellular matrix which is responsible for the biomechanical properties of cartilage tissue.

What is the function of bone and cartilage?

Cartilage and bone are specialised connective tissues that provide the body with mechanical support and protection. Both tissues have some common features in that they provide a unique combination of rigid yet plastic living tissue.

What is matrix of cartilage?

The matrix of cartilage is made up of glycosaminoglycans proteoglycans collagen fibers and sometimes elastin. … Cartilage is composed of specialized cells called chondrocytes that produce a large amount of collagenous extracellular matrix abundant ground substance that is rich in proteoglycan and elastin fibers.

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What is the main purpose of extracellular matrix surrounding osteocytes?

The main purpose of the extracellular matrix surrounding osteocytes is providing BONE STRENGTH. The extracellular matrix is deposited by action of the osteoblasts cells.

Which compound composes the bone matrix?

protein calcium and phosphorous are the kind of compound compose to bone matrix. The ligament is the tissue that connects two bones cartilage is another type of connective tissue that has a solid matrix.

Is the organic component of the matrix in developing or repairing bone?


The organic component of the matrix in developing or repairing bone is called osteoid.

What is the purpose of osteoblasts?

Osteoblasts are specialized mesenchymal cells that synthesize bone matrix and coordinate the mineralization of the skeleton. These cells work in harmony with osteoclasts which resorb bone in a continuous cycle that occurs throughout life.

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